Test guide

Antineutrophil Cytoplasmic Antibodies (ANCA) Test

An ANCA test looks for antineutrophil cytoplasmic antibodies (ANCA) in a sample of your blood. Antibodies are proteins that your immune system makes to fight foreign substances, such as viruses and bacteria. ANCAs, however, are autoantibodies, which are antibodies that attack your own healthy tissues and organs by mistake. This can lead to the development of an autoimmune disease .

For everyone & professionalsReviewed 2026-10-18

What it is for

An ANCA test can help diagnose: There are several types of vasculitis associated with ANCA. Each type can cause serious health problems depending on which blood vessels it affects. These types include: Source: MedlinePlus, National Library of Medicine. Medical test information is public domain. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.

Limitations

Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.

Also known as

  • ANCA antibodies, cANCA, pANCA, cytoplasmic neutrophil antibodies, serum, anticytoplasmic autoantibodies

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