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Glossary Term
Laboratory procedure in which single stranded nucleic acids are allowed to interact so that complexes, or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. (From Biology-online)
Glossary Term
Nucleotide Excision Repair (NER) mends DNA regions that contain chemical adducts, such as UV-induced thymine dimers or carcinogenic adducts, which distort the DNA helix and interfere with replication and transcription. NER is targeted to actively transcribed regions of the genome. During NER in eukaryotes, shape irregularities are detected by protein complexes that slide along the DNA molecule and induce cuts on each side of a lesion several nucleotides away. Removal of the damaged 25-30 nucleotide fragment is followed by repair synthesis and ligation.
Glossary Term
A statistical method to test if observations are significant or due to chance. It proposes that no statistical significance exists in a set of given observations and attempts to show that no variation exists between variables or that a single variable is no different than its mean. It is presumed to be true until statistical evidence nullifies it for an alternative hypothesis.
Glossary Term
The ratio of the odds of an event occurring in one group to the odds of it occurring in another group, or to a sample-based estimate of that ratio.
Glossary Term
A sequence of nucleotides in that contains no termination codons and so can potentially translate as a polypeptide chain.
Indicators
A naturally occurring amino acid found in meat, fish, dairy and eggs. Ornithine is one of the key reactants in the urea cycle that is responsible for 80% of the nitrogen excretion in the body. Ornithine enhances liver function and helps detoxify harmful substances.
Glossary Term
The concentration of osmoles of solute per kilogram of solvent present in a sample.
Tests
The determination of the osmoles of solute per kilogram of solvent present in a sample.
Tests
The determination of the amount of osteopontin present in a sample.
Glossary Term
An observation in a data set that is numerically distant from the rest of the data.
Tests
The determination of the amount of oxalate present in a sample.
Tests
The determination of the maximum amount of oxygen that can be combined chemically with hemoglobin in a volume of blood.
