Article
Research record from BMC Infect Dis, 2026-04-29. PMID 42056897.
Article
What drives NAT yield-testing economics for mid-size blood banks: pooling strategy, yield-window claims, workflow integration, and the contract points worth verifying.
Article
Research record from Cochrane Database Syst Rev, 2026-10-09. PMID 42852683.
Glossary Term
A reaction that contains all reagents except sample nucleic acid. Amplification in the NTC signals contamination of reagents or the environment, so NTC behavior is one of the first run-validity checks in any qPCR run log.
Pcr Terms
Article
Research record from Int J Infect Dis, 2026-03-20. PMID 41866059.
Glossary Term
Any of various amplification and detection strategies applied to detection of virus contamination in donor blood. Specifically designed to detect recently infected individuals during the latency period before seroconversion.
Pcr Terms
Article
Research record from Signal Transduct Target Ther, 2026-09-07. PMID 42706252.
Glossary Term
The sample-preparation stage that lyses cells or virions and purifies DNA/RNA before amplification. Extraction quality (yield, purity, inhibitors removed) often limits assay performance more than the PCR itself, and it defines required instruments and hands-on time in a workflow.
Extraction Methodology
Glossary Term
Laboratory procedure in which single stranded nucleic acids are allowed to interact so that complexes, or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. (From Biology-online)
Pcr Terms
Article
Research record from Sex Transm Dis, 2026-03-26. PMID 41885439.
Glossary Term
An enzymatic pre-treatment in nucleic-acid extraction that degrades proteins and nucleases, releasing nucleic acids from clinical material before binding, wash, and elution steps.
Extraction Methodology
Article
Research record from Cureus, 2026-04-02. PMID 42099359.