Test guide
Mixed Lymphocyte Reaction Test
An assay that measures the proliferative response of lymphocytes from one individual when they are exposed to inactivated lymphocytes from another individual. The reaction can be performed on lymphocytes from the same individual (auto-MLR), from different individuals of the same species (allo-MLR), or individuals from different species (xeno-MLR). It is used to evaluate the potential for graft-versus-host or host-versus-graft reactions during transplantation procedures involving mismatched tissue types or individuals.
What it is for
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16790. Unmodified NCI definition, CC BY 4.0. Source identity and classification checked automatically on 2026-10-20.
Limitations
Terminology reference for a laboratory procedure. The source definition does not establish routine clinical availability, validated specimen types, reference intervals, product authorization or suitability for an individual. Consult the performing laboratory for its validated method and interpretation.
Also known as
- Mixed Lymphocyte Culture
- Mixed Lymphocyte Reaction Test
- Mixed T Cells, B Cells
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