Test guide
CCP Antibody Test
This test looks for CCP (cyclic citrullinated peptide) antibodies in your blood. CCP antibodies, also called anti-CCP antibodies, are a type of antibody called autoantibodies. Antibodies and autoantibodies are proteins made by the immune system :
What it is for
A CCP antibody test is used to help diagnose or rule out rheumatoid arthritis. It's often done along with or after a rheumatoid factor (RF) test . Rheumatoid factors are another type of autoantibody. RF tests used to be the main test to help diagnose rheumatoid arthritis. However, RF factors can be found in people with other autoimmune diseases and even in some healthy people. And some people with RA have little to no RF factors. Doing both tests provides a more accurate diagnosis than only using RF testing results. Source: MedlinePlus, National Library of Medicine. Medical test information is public domain. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Limitations
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also known as
- Cyclic citrullinated peptide antibody, anticitrullinated peptide antibody, citrulline antibody, anti-cyclic citrullinated peptide, anti-CCP antibody, ACPA
Reviewed products
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