National Cancer Institute (source definition)
Plaque Reduction Neutralization Assay
A serological test that measures the ability of antibodies in specific concentrations of serum to prevent the formation of plaques in a cell monolayer when combined with a viral suspension.
Review and references
Automated source check (NCI definition)
2026-10-19
2026-10-19
professional use
References
- NCI Thesaurus 26.09d — Plaque Reduction Neutralization Assay (C172555)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C172555. NCI definition, reproduced without modification under CC BY 4.0.
- Fluorescence Reduction Neutralization Test: A Novel, Rapid, and Efficient Method for Characterizing the Neutralizing Activity of Antibodies Against Dengue Virus. — Curr Issues Mol Biol, 2025-02-21 (PMID 40136394; literature)
What it is
A serological test that measures the ability of antibodies in specific concentrations of serum to prevent the formation of plaques in a cell monolayer when combined with a viral suspension.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C172555. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.