National Cancer Institute (source definition)
Next Generation Sequencing
Technologies that facilitate the rapid determination of the nucleotide sequence of large numbers of strands or segments of DNA or RNA.
Review and references
Automated source check (NCI definition)
2026-10-18
2026-10-27
professional use
References
- NCI Thesaurus 26.09d — Next Generation Sequencing (C101293)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C101293. NCI definition, reproduced without modification under CC BY 4.0.
- Microfluidic approaches to next- generation sequencing library preparation: innovations, clinical integration and point-of-care settings. — Expert Rev Mol Diagn, 2026-10-07 (PMID 42802333; literature)
- Potential clinical actionability of metagenomic next-generation sequencing for antimicrobial stewardship for urinary tract infections: a retrospective, single-centre, BI-Biotia UTI cohort study. — Int J Infect Dis, 2026-10-14 (PMID 42874851; literature)
- Driver mutation profiling by next-generation sequencing predicts survival and recurrence after curative-intent resection for pancreatic ductal adenocarcinoma: a genomic cohort study. — Clin Transl Oncol, 2026-10-13 (PMID 42870132; literature)
- Next-Generation Sequencing to Identify Genetic Causes of Chinese Patients Affected With Non-retinal Developmental Eye Disorders. — Hum Mutat, 2026-10-16 (PMID 42891061; literature)
- Quantifying the diagnostic time gap in precision oncology: A retrospective analysis of potential time savings from same-day cartridge-based molecular testing versus next-generation sequencing in cytology specimens. — PLoS One, 2026-10-16 (PMID 42886752; literature)
- Analysis of CCR2 gene variants in patients with sarcoidosis using targeted next-generation sequencing: a case-control study. — Mol Biol Rep, 2026-10-20 (PMID 42900239; literature)
- Jeffrey's Insights: Next-generation sequencing for primary immunodeficiency diagnosis, 2019-2025. — J Hum Immun, 2026-10-20 (PMID 42900003; literature)
- Reader Response: Screening for Congenital Myasthenic Syndromes in Adults With Seronegative Myasthenia Gravis Using Next-Generation Sequencing. — Neurology, 2026-10-22 (PMID 42912863; literature)
- Editors' Note: Screening for Congenital Myasthenic Syndromes in Adults With Seronegative Myasthenia Gravis Using Next-Generation Sequencing. — Neurology, 2026-10-22 (PMID 42912862; literature)
- Diagnostic accuracy and clinical considerations of metagenomic next-generation sequencing in prosthetic joint infection: a systematic review and meta-analysis. — Eur J Clin Microbiol Infect Dis, 2026-10-23 (PMID 42918922; literature)
- From SELEX to Sequencing: Uncovering enriched Aptamers with Next-Generation Sequencing and Bioinformatics. — Bioinformatics, 2026-10-22 (PMID 42921901; literature)
- Author Response: Screening for Congenital Myasthenic Syndromes in Adults With Seronegative Myasthenia Gravis Using Next-Generation Sequencing. — Neurology, 2026-10-22 (PMID 42912860; literature)
What it is
Technologies that facilitate the rapid determination of the nucleotide sequence of large numbers of strands or segments of DNA or RNA.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C101293. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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