National Cancer Institute (source definition)
Magnetic Bead Separation
A cell-separation technique where magnetizable microspheres or beads are first coated with monoclonal antibody, allowed to search and bind to target cells, and are then selectively removed when passed through a magnetic field. Among other applications, the technique is commonly used to remove tumor cells from the marrow of patients who are to undergo autologous bone marrow transplantation.
Review and references
Automated source check (NCI definition)
2026-10-19
2026-10-19
professional use
References
- NCI Thesaurus 26.09d — Magnetic Bead Separation (C19304)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C19304. NCI definition, reproduced without modification under CC BY 4.0.
- Tyramide signal amplification integrated with magnetic bead separation to overcome the matrix effect and detect SAA protein in peripheral blood. — Analyst, 2026-08-10 (PMID 42359898; literature)
- Engineered eMutS based magnetic separation system for high-fidelity DNA synthesis. — Synth Syst Biotechnol, 2026-03-06 (PMID 42630670; literature)
- Magnetic separation coupled with gold nanoparticle-assisted hybridization chain reaction for simultaneous detection of exomiR-21 and exomiR-155. — Anal Chim Acta, 2025-11-11 (PMID 41352918; literature)
What it is
A cell-separation technique where magnetizable microspheres or beads are first coated with monoclonal antibody, allowed to search and bind to target cells, and are then selectively removed when passed through a magnetic field. Among other applications, the technique is commonly used to remove tumor cells from the marrow of patients who are to undergo autologous bone marrow transplantation.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C19304. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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