National Cancer Institute (source definition)
Loop-mediated Isothermal Amplification
A type of nucleic acid amplification test in which sample DNA is exposed to a single temperature in the presence of multiple sets of primers and a polymerase with replication and high strand displacement activity. This test negates the need for thermal cyclers and may be a low cost alternative to PCR.
Review and references
Automated source check (NCI definition)
2026-10-18
2026-10-31
professional use
References
- NCI Thesaurus 26.09d — Loop-mediated Isothermal Amplification (C102661)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C102661. NCI definition, reproduced without modification under CC BY 4.0.
- Development of loop-mediated isothermal amplification and recombinase polymerase amplification combined with lateral flow dipstick assay for the rapid detection of Salmon gill poxvirus. — J Virol Methods, 2026-10-08 (PMID 42849817; literature)
- Detection of Influenza D Virus using Reverse Transcription Loop-Mediated Isothermal Amplification. — Emerg Infect Dis, 2026-10-01 (PMID 42811284; literature)
- A cationic platinum nanocluster-based loop-mediated isothermal amplification platform with pretreatment by magnetic nanoparticles for colorimetric and quantitative detection of MRSA from clinical samples. — Analyst, 2026-09-29 (PMID 42689457; literature)
- A solid-state heater-imager for quantitative evaluation of colorimetric isothermal nucleic acid amplification on paper. — Lab Chip, 2026-09-16 (PMID 42578606; literature)
- Novel Target for Pathogenic Leptospira Detection via Colorimetric Loop-Mediated Isothermal Amplification (LAMP): Development, Validation, and Comparative Analysis. — J Clin Lab Anal, 2026-10-14 (PMID 42876165; literature)
- Detection of Plasmodium vivax and Plasmodium falciparum using colorimetric loop-mediated isothermal amplification from dried blood spots collected in active and passive malaria surveillance in the Peruvian Amazon. — PLoS Negl Trop Dis, 2026-10-13 (PMID 42868181; literature)
- Development of loop-mediated isothermal amplification (LAMP) combined with a lateral flow dipstick DNA biosensor for detection of α thalassemia 1 [Southeast Asia (SEA), --SEA deletion]. — PLoS One, 2026-10-12 (PMID 42862843; literature)
- From Speed and Sensitivity to Robust Reliability: Addressing the Detection Bias of Loop-Mediated Isothermal Amplification (LAMP) in Food Authentication. — Foods, 2026-09-29 (PMID 42883594; literature)
- Validation of a Rapid Loop-Mediated Isothermal Amplification-Based Test for the Detection of Shigella from Rectal Swab. — Am J Trop Med Hyg, 2026-10-20 (PMID 42901155; literature)
- Diagnostic performance of a loop-mediated isothermal amplification test for the diagnosis of human and cat sporotrichosis in two highly endemic areas in Brazil: insights from a real-world, field-based evaluation. — Braz J Microbiol, 2026-10-21 (PMID 42905351; literature)
- A rapid field-deployable transgenic event detection system in genetically modified (GM) cotton using annealing curve based multiplex real-time loop-mediated isothermal amplification (LAMP). — Talanta, 2026-10-23 (PMID 42927720; literature)
- Rapid Detection of Rhizoctonia solani in Turfgrass and Soil Using a Loop-Mediated Isothermal Amplification-Based Point-of-Care Testing System. — Lett Appl Microbiol, 2026-10-29 (PMID 42954389; literature)
- Pathogen Spectrum and Epidemiological Characteristics Detected by Multiplex Loop-Mediated Isothermal Amplification in Elderly Patients in Guangzhou. — J Vis Exp, 2026-10-27 (PMID 42949203; literature)
What it is
A type of nucleic acid amplification test in which sample DNA is exposed to a single temperature in the presence of multiple sets of primers and a polymerase with replication and high strand displacement activity. This test negates the need for thermal cyclers and may be a low cost alternative to PCR.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C102661. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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