National Cancer Institute (source definition)
In Situ Hybridization
Use of a DNA or RNA probe to detect the presence of complementary sequences in chromosomes, cells, or tissues.
Review and references
Automated source check (NCI definition)
2026-10-19
2026-10-27
professional use
References
- NCI Thesaurus 26.09d — In Situ Hybridization (C17562)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C17562. NCI definition, reproduced without modification under CC BY 4.0.
- Diagnostic Utility of USP6 RNA Chromogenic In Situ Hybridization in the Differential Diagnosis of Nodular Fasciitis and Aneurysmal Bone Cyst. — Am J Surg Pathol, 2026-10-09 (PMID 42850764; literature)
- Proof-of-Concept Evaluation of T-Cell Receptor Beta Constant Region 1 and 2 Transcript in Situ Hybridization for Clonality Assessment in Mycosis Fungoides. — J Cutan Pathol, 2026-10-15 (PMID 42881119; literature)
- Fusion Detection in Microsecretory Adenocarcinoma and Mucoepidermoid Carcinoma Using Chromogenic RNA In Situ Hybridization: A Promising Alternative to DNA-Based Fluorescence In-Situ Hybridization. — Mol Carcinog, 2026-10-25 (PMID 42927643; literature)
- Fluorescence in situ hybridization reveals endophytic and epiphytic root colonization of the novel plant growth-promoting bacterium Citrobacter sedlakii CESi7. — Biosci Biotechnol Biochem, 2026-10-23 (PMID 42913500; literature)
What it is
Use of a DNA or RNA probe to detect the presence of complementary sequences in chromosomes, cells, or tissues.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C17562. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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