National Cancer Institute (source definition)
Affinity Chromatography
A chromatographic separation technique based on the ability of proteins to bind specific ligands reversibly.
Review and references
Automated source check (NCI definition)
2026-10-19
2026-10-27
professional use
References
- NCI Thesaurus 26.09d — Affinity Chromatography (C16432)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16432. NCI definition, reproduced without modification under CC BY 4.0.
- A CotB1p-mediated one-step immobilization strategy for constructing GPCR affinity chromatography to screen multi-target natural product ligands. — J Pharm Biomed Anal, 2026-09-17 (PMID 42800465; literature)
- Analysis by microscale affinity chromatography of humic acid interactions with pharmaceutical micropollutants. — J Chromatogr B Analyt Technol Biomed Life Sci, 2026-09-10 (PMID 42743902; literature)
- Affinity Chromatography With Selective Nucleic Acid Hybridization: Direct Coupling With Size Exclusion Chromatography. — J Sep Sci, 2026-10-01 (PMID 42888955; literature)
- Electrostatic inversion in pH-gradient antigen affinity chromatography: The selectivity bias for deamidated trastuzumab proteoforms. — J Chromatogr A, 2026-10-17 (PMID 42925825; literature)
What it is
A chromatographic separation technique based on the ability of proteins to bind specific ligands reversibly.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16432. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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