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Tests
The determination of the amount of organisms that are vancomycin-resistant, and are not assigned to the species level but are assigned to the Enterococcus genus level in a biological sample.
Article
Research record from Clin Chem Lab Med, 2026-08-12. PMID 42578267.
Article
Research record from J Pharm Technol, 2026-03-30. PMID 41924397.
Indicators
A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.
Tests
An assay for susceptibility of a microorganism to a antimicrobial agent that uses a circular paper disk impregnated with vancomycin.
