Tests
Soluble Tumor Necrosis Factor Receptor Superfamily Member 4 Measurement
The determination of the amount of soluble tumor necrosis factor receptor superfamily member 4 in a sample.
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Tests
The determination of the amount of soluble tumor necrosis factor receptor superfamily member 4 in a sample.
Indicators
Tumor necrosis factor (233 aa, ~26 kDa) is encoded by the human TNF gene. This protein is involved in the induction of cytokine expression, the stimulation of cell proliferation and the positive regulation of cell differentiation.
Tests
The determination of the tumor necrosis factor receptor 1 present in a sample.
Indicators
Tumor necrosis factor receptor superfamily member 11B (401 aa, ~46 kDa) is encoded by the human TNFRSF11B gene. This protein plays a role in the negative regulation of both osteoblast differentiation and bone resorption.
Tests
The determination of the amount of soluble TNF receptor type I present in a sample.
Tests
The determination of the amount of tumor necrosis factor receptor superfamily member 1B present in a sample.
Tests
The determination of the amount of total tumor necrosis factor superfamily member 12 present in a sample.
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Technology
Comparative genomic hybridization (CGH) is a technique that allows the detection of losses and gains in DNA copy number across the entire genome without prior knowledge of specific chromosomal abnormalities. Comparative genomic hybridization utilizes the hybridization of differentially labeled tumor and reference DNA to generate a map of DNA copy number changes in tumor genomes. Comparative genomic hybridization is an ideal tool for analyzing chromosomal imbalances in archived tumor material and for examining possible correlations between these findings and tumor phenotypes. (from Ried et al. J Mol Med 1997 75:801-14)