Indicators
A secreted antigen derived from two nearly identical cytoplasmic glycoproteins of the serpin family, serpin B3 (SCCA-1) and serpin B4 (SCCA-2). These proteins are specifically expressed in normal squamous epithelia and are present at elevated concentrations in the serum of subjects with squamous cell carcinoma and certain inflammatory and autoimmune diseases. This antigen was first described in squamous cell cervical carcinoma; it is currently used as a nonspecific tumor marker for the presence, staging and monitoring of the disease course for squamous cell carcinomas of the head and neck, cervix, esophagus, anus and lung.
Article
Research record from Mod Pathol, 2026-03-03. PMID 41786210.
Tests
The determination of the ratio of columnar epithelial cells compared to non-squamous epithelial cells present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the ratio of eosinophils compared to non-squamous epithelial cells present in a sample. The measurement may be expressed as a ratio or percentage.
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Tests
The determination of the ratio of epithelial cells compared to non-squamous epithelial cells present in a sample. The measurement may be expressed as a ratio or percentage.
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Tests
The determination of the ratio of lymphocytes compared to non-squamous epithelial cells present in a sample. The measurement may be expressed as a ratio or percentage.
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Tests
The determination of the ratio of macrophages compared to non-squamous epithelial cells present in a sample. The measurement may be expressed as a ratio or percentage.
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Tests
The determination of the ratio of neutrophils compared to non-squamous epithelial cells present in a sample. The measurement may be expressed as a ratio or percentage.
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Tests
The determination of the amount of non-squamous epithelial cells present in a sample.
For professionals
Article
Research record from Cancer Treat Res Commun, 2026-08-29. PMID 42667845.
Tests
The determination of the ratio of the squamous epithelial cells compared to the total cells present in a sample. The measurement may be expressed as a ratio or percentage.
For professionals
Tests
The determination of the number of squamous transitional epithelial cells present in a urine sample.
For professionals
