Glossary Term
RNA Splicing
Removal of introns from mRNA precursors and the reattachment or annealing of exons.
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Glossary Term
Removal of introns from mRNA precursors and the reattachment or annealing of exons.
Glossary Term
The paired nucleotides in a DNA or RNA sequence.
Glossary Term
A storage facility of biospecimens that includes tissue samples, fluids, and molecular derivatives such as DNA, RNA, and proteins. The biorepository has stringent guidelines regarding the standardized collection, handling, storage, and documentation of biological specimens.
Glossary Term
Single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase.
Glossary Term
A sequence of single-stranded RNA that forms a covalently closed continuous loop.
Glossary Term
A specific sequence of three adjacent bases on a strand of DNA or RNA that provides genetic code information for a particular amino acid.
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An RNA complex consisting of two complementary base-paired strands of RNA.
Glossary Term
The sequences of a gene that are present in the final, mature, spliced messenger RNA molecule from that gene.
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Typically involves transcription of genetically encoded information into an intermediary message (messenger RNA) and subsequent translation into a functional protein.
Glossary Term
The complete genomic content of an organism, and possibly the full DNA sequence of that organism. It is contained in a set of chromosomes in eukaryotes, a single chromosome in bacteria, or a DNA or RNA molecule in viruses.
Glossary Term
Non-coding, intervening sequences of DNA that are transcribed, but are removed from within the primary gene transcript and rapidly degraded during maturation of messenger RNA.
Glossary Term
A molecule of RNA 200-17000 nucleotides in length that is transcribed by non-protein coding areas of DNA. These ribonucleotides may play a role in a variety of biological processes.