Glossary Term
Intron
PCR TermsEN
Definition
Non-coding, intervening sequences of DNA that are transcribed, but are removed from within the primary gene transcript and rapidly degraded during maturation of messenger RNA.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C13249. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Intervening SequenceIntronIntronic
References
- NCI Thesaurus 26.09d — Intron (C13249)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C13249. NCI definition, reproduced without modification under CC BY 4.0.
- The Mitochondrial PPR Protein AS3 Interacts with NPPR2 to Facilitate trans-Splicing of nad1 Intron 1 and Ensure Kernel Development in Maize. — Plant Sci, 2026-10-17 (PMID 42892336; literature)
- An intron retention-derived secreted Endoglin Isoform as a circulating biomarker in pancreatic ductal adenocarcinoma. — Neoplasia, 2026-10-09 (PMID 42854278; literature)
- Intron retention regulates STAT2 function and associates with immunotherapy response in lung cancer. — Science, 2026-10-22 (PMID 42912151; literature)
- MAJIQ V3: Scalable and accurate RNA splicing analysis with splicegraph algebra and improved intron retention modeling. — NAR Genom Bioinform, 2026-10-21 (PMID 42909379; literature)
- A non-allelic homologous recombination-induced inversion in intron 22 of the F8 gene is causative for haemophilia A in a Weimaraner male dog. — PLoS One, 2026-10-26 (PMID 42932266; literature)