Indicators
Lipoprotein Lipase
Lipoprotein lipase (475 aa, ~53 kDa) is encoded by the human LPL gene. This protein is involved in the metabolism of triglycerides.
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Indicators
Lipoprotein lipase (475 aa, ~53 kDa) is encoded by the human LPL gene. This protein is involved in the metabolism of triglycerides.
Indicators
A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.
Indicators
An animal sterol found in the body tissues (and blood plasma) of vertebrates. It can be found in large concentrations within the liver, spinal cord, and brain. Cholesterol is an important component of the membranes of cells, providing stability. It is the major precursor for the synthesis of vitamin D, of the various steroid hormones, including cortisol, cortisone, and aldosterone in the adrenal glands, and of the sex hormones progesterone, estrogen, and testosterone. Cholesterol also has an important role for the brain synapses as well as in the immune system. In conditions featuring elevated low density lipoproteins (LDL), cholesterol often forms plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease.
Tests
The determination of the ratio of total cholesterol compared to high-density lipoprotein type cholesterol present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the amount of the average particle size of high-density lipoprotein in a sample.
Tests
The determination of the amount of high-density lipoprotein phospholipid present in a sample.
Indicators
The smallest and densest lipoproteins, containing a high proportion of protein. They are synthesized in the liver as empty proteins and they pick up cholesterol and increase in size as they circulate through the bloodstream. Because HDL can remove cholesterol from the arteries, and transport it back to the liver for excretion, they are seen as "good" lipoproteins.
Tests
The determination of the high density lipoprotein cholesterol and the low density lipoprotein cholesterol present in a sample.
Tests
The determination of the amount of high-density lipoprotein cholesterol present in a sample.
Tests
The determination of the ratio of the amount of intermediate density lipoprotein cholesterol compared to low density lipoprotein cholesterol present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the amount of intermediate density lipoprotein triglyceride in a sample.
Glossary Term
An isomer of propyl alcohol with antibacterial properties. Although the exact mechanism of isopropanol's disinfecting action is not known, it might kill cells by denaturing cell proteins and DNA, interfering with cellular metabolism, and dissolving cell lipo-protein membranes. Isopropanol is used in soaps and lotions as an antiseptic.