Indicators
ABL1 Gene
This gene is involved in cell adhesion, differentiation, division and stress response.
Loading
Loading
Search products, companies, tests, and guides — go from query to quote request in one place.
Indicators
This gene is involved in cell adhesion, differentiation, division and stress response.
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Indicators
This gene plays a role in body weight homeostasis and cellular proliferation. Mutations in the gene are associated with acute myeloid leukemia.
Indicators
This gene plays a role in cellular hematopoiesis and differentiations. Mutations in the gene are associated with several diseases, including acute myelogenous leukemia, gastrointestinal tumors, and mast cell disease.
Indicators
This gene is involved in transcriptional regulation and alterations in the gene are associated with acute lymphoblastic leukemia.
Indicators
This gene plays a role in mitogenic activities affecting mesenchymal cells and a translocation in the gene results in chronic myelomonocytic leukemia.
Indicators
This gene is involved in cell growth, proliferation, differentiation and migration. It also plays a role in apoptosis.