Indicator Explainer
PDGFRB Gene
This gene plays a role in mitogenic activities affecting mesenchymal cells and a translocation in the gene results in chronic myelomonocytic leukemia.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C24667. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — PDGFRB Gene (C24667)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C24667. NCI definition, reproduced without modification under CC BY 4.0.
- Cutaneous Juvenile Xanthogranuloma With MRC1::PDGFRB Gene Fusion: A Case Report. — Pediatr Dermatol, 2025-07-19 (PMID 40682442; literature)
- Novel PDGFRB Gene Fusions in Two Cases of Infantile Myofibromatosis. — Genes Chromosomes Cancer, 2025-01-01 (PMID 39873217; literature)
- The novel TERF2::PDGFRB fusion gene enhances tumorigenesis via PDGFRB/STAT5 signalling pathways and sensitivity to TKI in ph-like ALL. — J Cell Mol Med, 2024-02-01 (PMID 38323741; literature)