Indicators
ABL1 Gene
This gene is involved in cell adhesion, differentiation, division and stress response.
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Indicators
This gene is involved in cell adhesion, differentiation, division and stress response.
Indicators
This gene plays a role in signal transduction.
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This gene is involved in signal transduction and negative regulation of apoptosis. It also plays a role in glucose transport, glycogen synthesis, protein synthesis and neuronal survival.
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This gene plays a role in glucose homeostasis and the inhibition of apoptosis.
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This gene is involved in signal transduction and the inhibition of apoptosis.
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A broad-spectrum semi-synthetic aminoglycoside antibiotic, derived from kanamycin with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically locking 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex and misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. This agent is usually used in short-term treatment of serious infections due to susceptible strains of Gram-negative bacteria.
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Human ANPEP wild-type allele is located within 15q25-q26 and is approximately 30 kb in length. This allele, which encodes aminopeptidase N protein, is involved in the modulation of peptide hydrolysis and human infection by cytomegalovirus and coronavirus.
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An antiphospholipid autoantibody that reacts with beta-2-glycoprotein 1, and a member of family of autoantibodies that cause antiphospholipid antibody syndrome and may be found in system lupus erythematosus.
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An autoantibody that recognizes histidyl-tRNA synthetase, cytoplasmic protein.
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An antinuclear antibody directed against a 47 kDa RNA-binding protein in the nucleus. They can be associated with Sjogren syndrome and system lupus erythematosus. Maternal anti-La antibody positivity can be associated with neonatal lupus.
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An antinuclear antibody directed against U1 snRNP, that is strongly associated with mixed connective tissue disease and commonly detected in lupus.
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An antinuclear antibody directed against 52 or 60 kDa RNA-binding proteins in the nucleus. They can be associated with multiple autoimmune disorders, primarily Sjogren syndrome and system lupus erythematosus. Maternal anti-Ro antibody positivity can be associated with neonatal lupus.