Tests
A free light chains test measures the level of free light chains in your blood. Light chains are proteins made by plasma cells, a type of white blood cell. Light chains usually link up with other proteins called heavy chains. Together, the light and heavy chains make immunoglobulins, also called antibodies. Antibodies are proteins that your immune system makes to fight germs such as viruses and bacteria .
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Technology
Electron microscopy involving an aqueous suspension of a sample which is applied in an extremely thin film to a grid, frozen in liquid nitrogen and maintained in this state by means of a special mount. The imaging of frozen-hydrated molecules and organelles permits the best possible resolution closest to the living state, free of chemical fixatives or stains.
Diagnostic Methods
Product
Immunoassay
Product
Immunoassay
Product
Immunoassay
Technology
A DNA sequencing method that uses a "sequencing by synthesis" strategy. The strand complementary to a template is synthesized a single base at a time through the sequential addition of individual solutions of each base. Incorporation of a base into the growing strand generates free pyrophosphate that is detected as light, as generated by a luciferase-catalyzed reaction.
Diagnostic Methods
Article
Research record from Zhonghua Yu Fang Yi Xue Za Zhi, 2026-05-01. PMID 42128686.
Article
Research record from J Chromatogr A, 2026-04-09. PMID 41985367.
Article
Research record from J Liq Biopsy, 2026-10-06. PMID 42893057.
Article
Research record from Reprod Sci, 2026-08-04. PMID 42552471.
Indicators
The orally bioavailable alpha form of the naturally-occurring fat-soluble vitamin E, with potent antioxidant and cytoprotective activities. Upon administration, alpha-tocopherol neutralizes free radicals, thereby protecting tissues and organs from oxidative damage. Alpha-tocopherol gets incorporated into biological membranes, prevents protein oxidation and inhibits lipid peroxidation, thereby maintaining cell membrane integrity and protecting the cell against damage. In addition, alpha-tocopherol inhibits the activity of protein kinase C (PKC) and PKC-mediated pathways. Alpha-tocopherol also modulates the expression of various genes, plays a key role in neurological function, inhibits platelet aggregation and enhances vasodilation. Compared with other forms of tocopherol, alpha-tocopherol is the most biologically active form and is the form that is preferentially absorbed and retained in the body.
Article
Research record from J Clin Pathol, 2026-08-20. PMID 42331602.