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Research record from J Vis Exp, 2026-03-13. PMID 41911173.
Article
Research record from Mass Spectrom Rev, 2026-08-22. PMID 42630127.
Glossary Term
A sequential p-value procedure that controls expected false discovery rate.
Article
A composite case study on MRSA screening: how late reporting happens, the diagnostic decisions that close the gap, and how to verify the fix with measurable targets.
Article
Research record from Mol Genet Genomics, 2026-03-17. PMID 41843205.
Glossary Term
A statistical method used for multiple testing corrections to control the expected proportion of false positives (Type I error) among rejected tests or hypotheses. It is less stringent than other multiple testing corrections and thereby, will allow a percentage of false positives.
Glossary Term
The minimum False Discovery Rate (FDR) value required for a test to be considered significant.
Glossary Term
Ubiquitin is a family of widely distributed proteins found in all eukaryotes that contain a highly conserved sequence of 76 amino acids identical in organisms from humans to insects. It participates in diverse cellular functions by conjugation to other proteins through its carboxy terminus. Ubiquitination is associated with many highly regulated biological events including protein degradation, chromatin remodelling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. Protein ubiquitination regulates the half-lives of many proteins by targeting them for degradation. Newly discovered families of ubiquitination and deubiquitination enzymes participate in these processes. Ubiquitination enzymes may provide new therapeutic targets and ways of intervention in many human diseases.