Indicators
A synthetic form of dehydroepiandrosterone with potential chemopreventive activity. Produced endogenously, dehydroepiandrosterone (DHEA) is an intermediate in the conversion of cholesterol to androgens and estrogens. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they may result in both direct and indirect physiologic effects. Direct effects include GABA-a receptor complex and NMDA receptor modulation, and enhanced pancreatic beta cell insulin secretion and antiglucocorticoid activities. (NCI04)
Indicators
This gene is involved in repression of transcription. It plays a role in the formation of pre-plasma memory B cells and immunoglobulin-secreting plasma cells.
Glossary Term
A quantitative representation of the degree of accuracy necessary for or associated with a particular action.
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Article
Research record from J Cancer Res Clin Oncol, 2026-04-02. PMID 41927843.
Glossary Term
An expression of the likelihood that a given test result correlates with the presence or absence of disease.
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Tests
The determination of the amount of pregnancy-associated plasma protein-A present in a sample.
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Glossary Term
Chemicals that are added to drug products to prolong shelf life and maintain sterility. Protection of formulations, especially aqueous solutions, against microbial growth requires use of either antibacterial or antifungal preservatives. Generally, such agents are active against either bacteria or fungi but a few are active against both. The antimicrobials include but not limited to chlorobutanol, benzyl alcohol, sodium benzoate, sorbic acid, and phenol. The antioxidizing agents include butylated hydroxytoluene, hydroxyanisole, propyl gallate, and sulfites. The necessary addition of preservatives for both safety and economy sometimes has been associated with significant adverse effects in certain patient populations.
Pcr Terms
Glossary Term
The ratio (for a given time period) of the number of occurrences of a disease or event to the number of units at risk in the population.
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Indicators
This gene plays a role in the regulation of protein kinase A.
Glossary Term
General term for a piece of DNA or RNA corresponding to a gene or sequence of interest, that has been labelled either radioactively or with some other detectable molecule, such as biotin, digoxygenin or fluorescein. As stretches of DNA or RNA with complementary sequences will hybridize, a probe will label viral plaques, bacterial colonies or bands on a gel that contain the gene of interest.
Pcr Terms
Indicators
A biomarker rising markedly in systemic bacterial infection — decision support for antibiotic pathways, not a diagnosis by itself.
Glossary Term
A program for the determination of laboratory performance where individual labs perform the same test on the same or similar items or materials, with the results from each lab compared and evaluated.
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