Glossary Term
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A sequence of nucleotides in that contains no termination codons and so can potentially translate as a polypeptide chain.
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Glossary Term
A sequence of nucleotides in that contains no termination codons and so can potentially translate as a polypeptide chain.
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The concentration of osmoles of solute per kilogram of solvent present in a sample.
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An observation in a data set that is numerically distant from the rest of the data.
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A method used to test whether the mean difference between pairs of measurements in a related group are significant.
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In statistical inference procedures (hypothesis tests and confidence intervals), parametric procedures are those that incorporate assumptions about population parameters.
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Quantity of dimension one used to express on a scale from 0 to 14 the amount-of-substance concentration of hydrogen ion of dilute aqueous solution, calculated as the logarithm of the reciprocal of hydrogen-ion concentration in gram atoms per liter.
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A small-scale mutation in which a single nucleotide is exchanged for another. Mutagenic chemicals and mistakes in DNA replication may result in point mutations.
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A distribution function used to describe the occurrence of rare events or to describe the sampling distribution of isolated counts in a continuum of time or space. This special probability distribution can apply to the number of discrete independent random events occurring in a given interval when knowing their average rate of occurrence over a very long interval.
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Chemicals that are added to drug products to prolong shelf life and maintain sterility. Protection of formulations, especially aqueous solutions, against microbial growth requires use of either antibacterial or antifungal preservatives. Generally, such agents are active against either bacteria or fungi but a few are active against both. The antimicrobials include but not limited to chlorobutanol, benzyl alcohol, sodium benzoate, sorbic acid, and phenol. The antioxidizing agents include butylated hydroxytoluene, hydroxyanisole, propyl gallate, and sulfites. The necessary addition of preservatives for both safety and economy sometimes has been associated with significant adverse effects in certain patient populations.
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The ratio (for a given time period) of the number of occurrences of a disease or event to the number of units at risk in the population.
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A type of study in which participants are enrolled into the study before they develop the disease or outcome in question.
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An enzymatic pre-treatment in nucleic-acid extraction that degrades proteins and nucleases, releasing nucleic acids from clinical material before binding, wash, and elution steps.