Glossary Term
Ligase
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by forming a phosphodiester bond.
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Glossary Term
Major class of enzymes that catalyze the linking together of two molecules (EC class 6) for example DNA ligases that link two fragments of DNA by forming a phosphodiester bond.
Glossary Term
A molecule of RNA 200-17000 nucleotides in length that is transcribed by non-protein coding areas of DNA. These ribonucleotides may play a role in a variety of biological processes.
Tests
A proprietary PCR technique that uses a pool of primers to amplify a 450 bp region in the L1 region of the HPV genome. It is capable of detecting 37 high- and low-risk human papillomavirus genotypes.
Tests
A lipoprotein (a) test measures the level of lipoprotein (a) in your blood. A high level of lipoprotein (a) may mean you have a high risk for heart disease and stroke .
Glossary Term
A genetic variation where gain, loss, or exchange of DNA results in monoallelic loss of function mutations in a diploid cell. In the context of tumor suppressor genes, where a single copy is sufficient for functionality, loss of function for the second allele is associated with tumorigenesis.
Indicators
A lipoprotein that carries cholesterol around the body, for use by various cells. LDL transports cholesterol to the arteries and increased levels are associated with atherosclerosis, and thus myocardial infarctions and strokes. This is why cholesterol inside LDL lipoproteins is called bad cholesterol.
Indicators
A heterodimeric glycoprotein hormone secreted by the gonadotropic cells of the anterior pituitary gland. This hormone is involved in stimulation of testosterone production by Leydig cells in males and triggering ovulation and corpus luteum development in females.
Tests
A quantitative measurement of the amount of magnesium present in a sample.
Glossary Term
A purification method in which nucleic acids bind to paramagnetic beads and are collected with a magnet through wash steps. It automates well, which is why most high-throughput extraction platforms are bead-based; compare deck footprint and sample capacity when shortlisting systems.
Tests
A clot detection method that uses a manual means (visual discernment) to detect the presence and/or quantify the formation of a thrombus in a specimen.
Indicators
This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation.
Indicators
This gene plays a role in both protein phosphorylation and signal transduction.