Indicators
PTPN11 Gene
This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and gene transcription.
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Indicators
This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and gene transcription.
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This gene is involved in cell growth, proliferation, differentiation and migration. It also plays a role in apoptosis.
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This gene is involved in the regulation of cell differentiation, growth and proliferation.
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Immature erythrocytes that have just undergone extrusion of their cell nucleus. They still contain some organelles that gradually decrease in number as the cells mature.
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The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.
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A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)
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This gene plays a role in chromatin remodeling, cell cycle control and regulation of transcription.
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This gene is involved in embryonic development and in the determination of cell fate.
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A secreted antigen derived from two nearly identical cytoplasmic glycoproteins of the serpin family, serpin B3 (SCCA-1) and serpin B4 (SCCA-2). These proteins are specifically expressed in normal squamous epithelia and are present at elevated concentrations in the serum of subjects with squamous cell carcinoma and certain inflammatory and autoimmune diseases. This antigen was first described in squamous cell cervical carcinoma; it is currently used as a nonspecific tumor marker for the presence, staging and monitoring of the disease course for squamous cell carcinomas of the head and neck, cervix, esophagus, anus and lung.
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This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
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This gene is involved in signal transduction and activation of transcription. It plays a role in the immune response via stimulation of T-cell proliferation.
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This gene plays a role in cell cycle regulation. It is also putatively involved in glucose production.