Article
The Detection of BRCA1 and BRCA2 Mutations in Saudi Females with Breast Cancer in Al-Madinah Province by Next Generation Sequencing.
Research record from Clin Lab, 2026-10-01. PMID 42847947.
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Article
Research record from Clin Lab, 2026-10-01. PMID 42847947.
Article
Research record from Cancer Treat Res Commun, 2026-04-22. PMID 42172690.
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A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04)
Glossary Term
The lowest limit at which something becomes detectable or relevant.
Tests
The determination of the ratio of the biological activity of thrombin dependent coagulation in a subject's specimen when compared to the same activity in a control specimen. The measurement may be expressed as a ratio or percentage.
Tests
A measurement of the Timothy grass (Phleum pretense) pollen IgA in a biological specimen.
Tests
The determination of the amount of tissue plasminogen activator antigen present in a sample.
Tests
The determination of the amount of tissue polypeptide antigen present in a sample.
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Tissue-type plasminogen activator (562 aa, ~63 kDa) is encoded by the human PLAT gene. This protein plays a role in the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin.
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This gene may play a role in the regulation of apoptosis.
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An aminoglycoside antibiotic derived from Streptomyces tenebrarius with bacteriostatic activity. Following active transport into the cell, tobramycin binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, thereby inhibiting initiation of protein synthesis, consequently leading to bacterial cell death. In addition, tobramycin induces misreading of the mRNA template causing incorrect amino acids to be incorporated into the growing polypeptide chain, consequently interfering with protein elongation.
Indicators
This gene plays a role in both transcriptional regulation and limb development.