Indicators
TSC2 Gene
This gene plays a role in signal transduction and cell cycle control. It is involved in cell adhesion, differentiation, growth and migration.
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Indicators
This gene plays a role in signal transduction and cell cycle control. It is involved in cell adhesion, differentiation, growth and migration.
Glossary Term
A statistical hypothesis test that controls directional errors if rejection of a hypothesis is the result of a directional decision. The two-sided test has less statistical power than the one-sided test.
Tests
The determination of the ratio of the type 1 myeloid dendritic cells to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of type 4 myeloid dendritic cells to leukocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Indicators
This gene is involved in RNA binding and pre-mRNA splicing.
Tests
The determination of the amount of ubiquitin-like protein ISG15 present in a sample.
Glossary Term
Ubiquitin is a family of widely distributed proteins found in all eukaryotes that contain a highly conserved sequence of 76 amino acids identical in organisms from humans to insects. It participates in diverse cellular functions by conjugation to other proteins through its carboxy terminus. Ubiquitination is associated with many highly regulated biological events including protein degradation, chromatin remodelling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. Protein ubiquitination regulates the half-lives of many proteins by targeting them for degradation. Newly discovered families of ubiquitination and deubiquitination enzymes participate in these processes. Ubiquitination enzymes may provide new therapeutic targets and ways of intervention in many human diseases.
Glossary Term
Short random nucleotide sequences that are ligated to each primer molecule during amplification of a nucleotide sample during library preparation to act as a unique tag. Their use helps to identify PCR duplicates in sequencing data.
Glossary Term
The product of so-called RNA genes; a functional RNA represents the final product of a gene rather than a transient molecule that will be translated into protein.
Tests
The determination of the amount of the norepinephrine metabolite, 3-methoxy-4-hydroxyphenylglycol, in a urine sample.
Tests
A quantitative measurement of the total amount of creatinine present in a sample of urine.
Glossary Term
The act of validating; finding or testing the truth of something.