Glossary Term
Avidity
Strength of binding, usually of a small molecule with multiple binding sites by a larger, particularly the binding of a complex antigen by an antibody.
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Glossary Term
Strength of binding, usually of a small molecule with multiple binding sites by a larger, particularly the binding of a complex antigen by an antibody.
Indicators
This gene is involved in signal transduction and plays a role in development.
Tests
A measurement of the B-lymphocyte to lymphocyte ratio in a sample.
Indicators
This gene plays a role in cellular response and is susceptible to oncogenic mutations in breast and ovarian cancers.
Glossary Term
Initiation of DNA base excision repair (BER) involves a DNA glycosylase that binds the altered deoxynucleoside in an extrahelical position and catalyzes cleavage of the base-sugar bond. Subsequently, an AP endonuclease or AP lyase activity incises the abasic site, followed by short-patch gap-filling, excision of the base-free sugar-phosphate residue, and ligation.
Glossary Term
The paired nucleotides in a DNA or RNA sequence.
Glossary Term
A starting point to which things may be compared.
Indicators
This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.
Indicators
This gene plays a role in the repression of gene transcription.
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Tests
A measurement of the bee mix antigen IgE antibody in a biological specimen.
Article
Research record from Trop Doct, 2026-10-16. PMID 42885714.