Glossary Term
Contaminated
The presence of any substance or organism that makes a preparation impure.
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Glossary Term
The presence of any substance or organism that makes a preparation impure.
Glossary Term
Variation in the number of copies of a particular sequence within the genetic material of an individual. Large-scale copy number polymorphisms are common and widely distributed in the human genome.
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The degree to which two or more quantities or events are linearly associated, a statistical relation between two or more variables such that systematic changes in the value of one variable are accompanied by systematic changes in the others.
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Problem associated with the degree to which an antibody or antigen participates in cross reactions.
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A statistical method of partitioning a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subsets are retained for subsequent use in confirming and validating the initial analysis.
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A substance that is used to protect from the effects of freezing, largely by preventing large ice crystals from forming.
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Enzymes that catalyze the hydrolytic cleavage of phosphodiester bond linkages in the DNA backbone. Deoxyribonucleases belong to a larger family of nucleases, which cleave DNA bases at various positions in the DNA backbone.
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The proportion of all the observations that have been classified correctly by the diagnostic procedures in given population, or using some diagnostic test, or by some medical institution or professional.
Glossary Term
The probability that a test will produce a true negative result when used on non-effected subjects as compared to a reference or "gold standard". The specificity of a test can be determined by calculating: number of true negative results divided by the sum of true negative results plus number of false positive results.
Glossary Term
A DNA sequencing technique in which a mixture of deoxynucleosidetriphosphates (dNTPs) and chain-terminating dNTPs, which are radioactively or fluorescently labeled, are combined within the reaction mixture. Once the reaction is complete, the DNA strands are separated by size, and the labeled chain terminating dNTPs can be read in sequence by the investigator or by a machine.
Glossary Term
A type of polymerase chain reaction technique in which the sample is fractionated, within which individual PCR reactions occur in each fraction.
Glossary Term
Any liquid or solid material used to lessen the strength or flavor of a solution or mixture of another ingredient.