Glossary Term
Deoxyribonuclease
Extraction MethodologyEN
Definition
Enzymes that catalyze the hydrolytic cleavage of phosphodiester bond linkages in the DNA backbone. Deoxyribonucleases belong to a larger family of nucleases, which cleave DNA bases at various positions in the DNA backbone.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16499. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Deoxyribonuclease
References
- NCI Thesaurus 26.09d — Deoxyribonuclease (C16499)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16499. NCI definition, reproduced without modification under CC BY 4.0.
- Pediatric patients with cancer exhibit increased neutrophil extracellular traps and reduced active deoxyribonuclease I: diagnostic, prognostic, and therapeutic opportunities. — Clin Exp Pediatr, 2026-08-19 (PMID 42705908; literature)
- Shikonin inhibits bladder cancer progression by targeting deoxyribonuclease 2 to suppress reticulon 3-dependent endoplasmic reticulum autophagy. — Phytomedicine, 2026-08-04 (PMID 42594755; literature)
- Effect of deoxyribonuclease I therapy on free circulating DNA level and gene methylation profile changes in patients with endometriosis: Proof of concept and preliminary data. — Sci Prog, 2026-07-01 (PMID 42599925; literature)
- Circulating neutrophil extracellular traps and deoxyribonuclease in gestational diabetes mellitus. — J Reprod Immunol, 2026-06-27 (PMID 42392015; literature)