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Indicators
A natural water-soluble vitamin (Vitamin C). Ascorbic acid is a potent reducing and antioxidant agent that functions in fighting bacterial infections, in detoxifying reactions, and in the formation of collagen in fibrous tissue, teeth, bones, connective tissue, skin, and capillaries. Found in citrus and other fruits, and in vegetables, vitamin C cannot be produced or stored by humans and must be obtained in the diet. (NCI04)
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Tests
A laboratory assay designed to detect elevated levels of (1,3)-beta-D-glucan in serum as an indication of infection by certain fungi species.
Glossary Term
A family of discrete probability density functions, which models systems that meet the following requirements: 1) the number of trials (n) is fixed; 2) there are only two outcomes for each trial, success or failure; 3) the outcome of each trial is independent; and 4) all trials have the same probability (p) of success. Binomial distributions show the likelihood of the number of successful trials versus the total number of trials.
Indicators
Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid. Growth factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tissue is higher than that of normal tissue.
Indicators
This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
Tests
The determination of the amount of Bordetella pertussis serotype Fimbrae 2/3 antibody present in a sample.
Indicators
An amino acid derivative. Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utilized as an energy substrate in all tissues except the brain.
Tests
The determination of cellular CD123 expression in a biospecimen.
Tests
The determination of cellular CD223 expression in a biological specimen.
Tests
The determination of the amount of CD33 expressing cells per unit present in a sample.
Tests
The determination of the amount of CCL23, chemokine (C-C motif) ligand 23, present in a sample.
