Indicators
CD274 Gene
This gene is involved in T cell activation and proliferation.
Loading
Loading
Search products, companies, tests, and guides — go from query to quote request in one place.
Indicators
This gene is involved in T cell activation and proliferation.
Indicators
A protein complex comprised of one T-cell surface glycoprotein CD3 delta chain (CD3D), one T-cell surface glycoprotein CD3 gamma chain (CD3G) and two T-cell surface glycoprotein CD3 epsilon chains (CD3E). CD3D, CD3G and CD3E are transmembrane proteins with one extracellular immunoglobulin domain and one intracellular ITAM domain. The CD3 complex is a T-cell co-receptor that noncovalently associates with either the disulfide bound heterodimeric alpha/beta T-cell receptor (TCR) or gamma/delta TCR and two copies of the accessory protein, T-cell surface glycoprotein CD3 zeta chain (CD247), which is a transmembrane protein with three ITAM domains. The TCR moiety of the TCR-CD3 complex binds to MHC and processed antigens on antigen presenting cells, which triggers phosphorylation of and cellular propagation of the signal by CD247 and the CD3 complex.
Tests
A CD4 count is a blood test that measures the number of CD4 cells in a sample of your blood. CD4 cells are a type of white blood cell that circulates throughout the body in the blood. They're also called CD4 T lymphocytes or "helper T cells." That's because they help fight infection by triggering your immune system to destroy viruses, bacteria, and other germs that may make you sick.
Tests
The determination of the ratio of CD4 T cells compared to lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the number of regulatory T-lymphocytes expressing CD4, CD25 and FOXP3 present in a sample.
Tests
The determination of the number of CD8 expressing T cells present in a sample.
Tests
The determination of a sub-population of cytotoxic central memory T-lymphocytes to a sub-population of cytotoxic central memory T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the number of a subpopulation of helper central memory T-lymphocytes in a sample.
Tests
The determination of the ratio of T-lymphocytes helper central memory sub-population to T-lymphocytes helper central memory present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of a sub-population of classical monocytes to all leukocytes that are not T-cells, B-cells, or natural killer cells, present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the ratio of the classical monocytes to all leukocytes that are not T-cells, B-cells, or natural killer cells, present in a sample. The measurement may be expressed as a ratio or percentage.
Article
Research record from Front Oncol, 2026-04-10. PMID 42038359.