Indicator Explainer
CD274 Gene
This gene is involved in T cell activation and proliferation.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C96022. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — CD274 Gene (C96022)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C96022. NCI definition, reproduced without modification under CC BY 4.0.
- Effect of siRNA-mediated knockdown of the PD-L1 (CD274) gene on DUSP gene family expression and potential clinical implications in gastric cancer. — Med Oncol, 2026-10-08 (PMID 42848101; literature)
- Structural insights into the impacts of non-synonymous single nucleotide polymorphisms in CD274 gene on the PD-1/PD-L1 interaction: An in silico approach. — Biochem Biophys Res Commun, 2025-09-18 (PMID 40983009; literature)
- Relationship between CD274 gene polymorphism and systemic lupus erythematosus risk in a Chinese Han population. — Int J Rheum Dis, 2024-01-01 (PMID 38287556; literature)
- The blockage signal for PD-L1/CD274 gene variants and their potential impact on lung carcinoma susceptibility. — Int Immunopharmacol, 2023-11-06 (PMID 37939515; literature)