Indicators
A hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cortex reducing post-tetanic potentiation at synapses. The reduction of potentiation prevents cortical seizure foci spreading to adjacent areas, stabilizing the threshold against hyperexcitability. In addition, this agent appears to reduce sensitivity of muscle spindles to stretch causing muscle relaxation.
Tests
The determination of the amount of plasmin alpha-2 antiplasmin complex in a sample.
For professionals
Indicators
Platelet-activating factor acetylhydrolase (441 aa, ~50 kDa) is encoded by the human PLA2G7 gene. This protein is involved in platelet-activating factor metabolism.
Tests
The determination of the amount of PMS1 homolog 2 present in a sample.
For professionals
Indicators
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
Indicators
Prostaglandin-H2 D-isomerase (190 aa, ~21 kDa) is encoded by the human PTGDS gene. This protein is involved in the conversion of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2).
Article
Research record from Medwave, 2026-05-15. PMID 42139648.
Article
Research record from Pediatr Blood Cancer, 2026-07-25. PMID 42500906.
Article
Research record from Clin Transl Oncol, 2026-06-25. PMID 42348103.
Article
Research record from Adv Parasitol, 2026-04-25. PMID 42203373.
Article
Research record from Clin Biochem, 2026-07-25. PMID 42501888.
Article
Research record from Int J Mol Sci, 2026-09-25. PMID 42883850.