Article
Evaluating Cell-Free DNA Quantification and Integrity in Breast Cancer Using Fluorometric, Electrophoretic and PCR-Based Platforms.
Research record from Methods Protoc, 2026-08-24. PMID 42776677.
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Article
Research record from Methods Protoc, 2026-08-24. PMID 42776677.
Article
Research record from Cancer Treat Res Commun, 2026-04-22. PMID 42048908.
Article
Research record from Front Mol Biosci, 2026-06-23. PMID 42416488.
Indicators
A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
Glossary Term
The sequences of a gene that are present in the final, mature, spliced messenger RNA molecule from that gene.
Tests
The determination of the amount of RNA encoded by a specific exon in a biological sample.
Glossary Term
An Exonuclease is a hydrolase (nuclease) that specifically catalyzes the hydrolysis of terminal phosphodiester bonds of deoxyribonucleotide or ribonucleotide chains, releasing mononucleotides.
Article
Research record from Cancer Cytopathol, 2026-05-01. PMID 42046206.
Article
Research record from Int J Mol Sci, 2026-07-30. PMID 42589489.
Indicators
This gene plays a role in chromatin remodeling and transcriptional regulation.
Indicators
An abnormality that refers to mutation of factor V Leiden, which is a variant of human factor V. It results in thrombophilia, deep vein thrombosis, and a slightly increased risk of miscarriage.
Tests
The determination of the ratio of the biological activity of factor X dependent coagulation in a subject's specimen when compared to the same activity in a control specimen. The measurement may be expressed as a ratio or percentage.