Glossary Term
Chromosome
A structure found in cells that is comprised of a strand of linearized double-stranded DNA plus proteins that package the DNA in a condensed coil form and regulate chromosomal function.
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Glossary Term
A structure found in cells that is comprised of a strand of linearized double-stranded DNA plus proteins that package the DNA in a condensed coil form and regulate chromosomal function.
Glossary Term
Problem associated with the degree to which an antibody or antigen participates in cross reactions.
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A substance that is used to protect from the effects of freezing, largely by preventing large ice crystals from forming.
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The proportion of all the observations that have been classified correctly by the diagnostic procedures in given population, or using some diagnostic test, or by some medical institution or professional.
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The probability that a test will produce a true negative result when used on non-effected subjects as compared to a reference or "gold standard". The specificity of a test can be determined by calculating: number of true negative results divided by the sum of true negative results plus number of false positive results.
Glossary Term
Any method that extracts and purifies DNA from biological samples, which can include the proper handling of biological samples prior to nucleic acid isolation, the separation of DNA from the rest of the components in the samples, and the storage of the DNA isolates.
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A WHO procedure that time-limits the listing of diagnostics (and other health products) for use in public-health emergencies when full prequalification is not yet available.
Glossary Term
Changes in the regulation of the expression of gene activity without alteration of genetic structure.
Glossary Term
Problem associated with the device incorrectly reporting that something has not been detected and may mislead the operator into not taking certain actions when action should be taken.
Glossary Term
Problem associated with the device incorrectly reporting that something has been detected and may mislead the operator to take certain actions.
Glossary Term
Refers to a process where a sample is preserved with formalin and then embedded into a paraffin block for sectioning.
Glossary Term
A mutation occurring within the protein-coding region of a gene which results in a shift in the reading frame of the encoded protein. Frameshift mutations often result in the premature truncation of a gene product.