Glossary Term
Geometric Mean
The n-th root of the multiple products of n values, as contrasted with the normally understood arithmetic mean.
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Glossary Term
The n-th root of the multiple products of n values, as contrasted with the normally understood arithmetic mean.
Glossary Term
Genomic instability associated with the presence of hypermutability in specific genetic marker regions resulting from defective DNA mismatch repair.
Glossary Term
The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.