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Article

Comparison of Colorimetric (Enzyme-Linked Immunosorbent Assay (ELISA)) and Chemiluminescent Immunoassay (CLIA) Methods for Detection of Dengue Nonstructural Protein 1 (NS1) Antigen in Acute Dengue Infection.

Research record from Cureus, 2026-05-17. PMID 42317899.

Article

Comparison of PCR-based high-resolution melting curve analysis and immunohistochemistry in detecting microsatellite instability in colorectal cancer: a retrospective consistency study.

Research record from PeerJ, 2026-08-17. PMID 42626667.

Article

CRISPR-based next-generation molecular diagnostics for bone infection.

Research record from Front Cell Dev Biol, 2026-06-17. PMID 42388979.

Article

Deficient Mismatch Repair Subtypes in Vietnamese Colorectal Cancer: Clinicopathologic Associations, Predictive Modeling, and IHC-PCR Concordance.

Research record from Cancer Manag Res, 2026-03-17. PMID 41869573.

Article

Diagnostic value of metagenomic next-generation sequencing in deep neck space infections: a retrospective study of 32 patients.

Research record from Front Cell Infect Microbiol, 2026-07-17. PMID 42539687.

Indicators

Dihydrotestosterone

The most potent androgen, required for sex development. Dihydrotestosterone is synthesized from testosterone in the prostate gland, testes, hair follicles and adrenal glands by 5-alpha reductase. Dihydrotestosterone exerts its action similar to testosterone, which binds to and activates specific nuclear androgen receptors. After translocation into the nucleus, the activated hormone-receptor complex binds to the androgen response elements on the DNA and activates gene expressions that are required for sex development. Dihydrotestosterone is responsible for the formation of male primary sex characteristics and most male secondary sex characteristics during puberty, such as muscular growth, facial and body hair growth, and deepening of the voice.

Article

Discovery of novel circular RNAs of the apoptosis-related BAX gene in breast cancer, by combining nanopore and next-generation sequencing.

Research record from Mol Genet Genomics, 2026-03-17. PMID 41843205.

Article

Editorial: Molecular diagnostics for cardiovascular rare disease.

Research record from Front Mol Biosci, 2026-03-17. PMID 41924352.

Indicators

Estradiol

The most potent form of the naturally occurring steroid sex hormone in humans, produced by ovary, placenta, testis, and in small amount by adrenal cortex. Estradiol binds to a specific intracellular estrogen receptor located in female organs, breasts, hypothalamus and pituitary. The receptor-ligand complex promotes gene expression necessary for the maintenance of fertility and secondary sexual characteristics in females. In addition, estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol.

Article

Evaluation of a 16S rRNA real-time PCR assay for detection of mycobacterium tuberculosis in comparison with GeneXpert MTB/RIF in a Vietnam hospital.

Research record from Diagn Microbiol Infect Dis, 2026-07-17. PMID 42497633.

Article

Functional Characterization of Myelodysplastic Syndrome by Multiparameter Flow Cytometry: The Clinical Synergy Between Ki-67 and Bcl-2 and Their Potential Role in Diagnostics and Personalized Therapy.

Research record from Cancers (Basel), 2026-08-17. PMID 42649960.

Tests

Gut-Homing Helper 17.1 T-Lymphocyte to Helper 17.1 T-Lymphocyte Ratio Measurement

The determination of the ratio of gut-homing helper 17.1 T-lymphocytes to total helper 17.1 T-lymphocytes present in a sample. The measurement may be expressed as a ratio or percentage.

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