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Indicators
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
Tests
The determination of the amount of MMP2-degraded type VI collagen fragment C6M in a sample.
Tests
A proprietary serology assay that can be used to measure IgG antibodies against the SARS-CoV-2 nucleocapsid protein (N).
Tests
A proprietary serology assay that can be used to measure IgM antibodies against the SARS-CoV-2 nucleocapsid protein (N).
Tests
A proprietary serology assay that can be used to measure IgG antibodies against the SARS-CoV-2 S1 spike receptor-binding domain (RBD).
Tests
A proprietary serology assay that can be used to measure IgA antibodies against the SARS-CoV-2 spike protein (S).
Indicators
This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1.
Article
Research record from J Mol Diagn, 2026-05-26. PMID 42202907.
Article
Research record from J Clin Microbiol, 2026-08-14. PMID 42599190.
Tests
The determination of the amount of MutS homolog 2 present in a sample.
Indicators
Neutrophil gelatinase-associated lipocalin (198 aa, ~23 kDa) is encoded by the human LCN2 gene. This protein may play a role in iron transport, apoptosis, and innate immunity.
Article
Research record from BMC Cancer, 2026-07-17. PMID 42464142.
