Indicators
SETD2 Gene
This gene is involved in epigenetic control of gene expression through histone methylation.
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Indicators
This gene is involved in epigenetic control of gene expression through histone methylation.
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A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. (NCI04)
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This gene plays a role in signal transduction and transcriptional activation. It is also involved in suppression of angiogenesis.
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This gene plays a role in chromatin remodeling, cell cycle control and regulation of transcription.
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This gene plays a role in chromatin remodeling and regulation of transcription.
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This gene is involved in chromatin remodeling and regulation of transcription.
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This gene plays a role in G protein-coupled receptor signal transduction and sonic hedgehog pathway activation.
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Soluble monocyte differentiation antigen CD14 is encoded by the human CD14 gene. This soluble protein may be used as a marker of monocyte activation and is derived either through cleavage that removes the glycophosphoinositol (GPI)-anchor from the membrane bound form of CD14 or as non-cleaved form secreted from the non-GPI-modified intracellular pool of CD14.
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This gene is involved in guanine nucleotide exchange.
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This gene is involved in embryonic development and in the determination of cell fate.
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This gene is involved in protein ubiquitination, which often leads to proteasomal degradation.
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This gene is involved in apoptosis, hormonogenesis, focal adhesion and the formation of intercellular junctions.