Tests
T-Cell Surface Glycoprotein CD5 Measurement
The determination of the amount of lymphocyte antigen T1/Leu-1 in a sample.
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Tests
The determination of the amount of lymphocyte antigen T1/Leu-1 in a sample.
Indicators
A macrolide isolated from Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent.
Tests
The determination of the amount of tissue plasminogen activator antigen present in a sample.
Glossary Term
Ubiquitin is a family of widely distributed proteins found in all eukaryotes that contain a highly conserved sequence of 76 amino acids identical in organisms from humans to insects. It participates in diverse cellular functions by conjugation to other proteins through its carboxy terminus. Ubiquitination is associated with many highly regulated biological events including protein degradation, chromatin remodelling, heat shock, cell cycle progression, differentiation, antigen presentation, retrovirus assembly, apoptosis, signal transduction, transcriptional activation, biological clocks, receptor down regulation, and endocytosis. Protein ubiquitination regulates the half-lives of many proteins by targeting them for degradation. Newly discovered families of ubiquitination and deubiquitination enzymes participate in these processes. Ubiquitination enzymes may provide new therapeutic targets and ways of intervention in many human diseases.
Tests
The determination of the amount of Ulmus americana pollen antigen IgE antibody present in a sample.
Indicators
5'-nucleotidase (574 aa, ~63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides.
Indicators
An autoantibody that recognizes histidyl-tRNA synthetase, cytoplasmic protein.
Tests
A quantitative measurement of aspartate aminotransferase present in a sample.
Tests
The determination of cellular CD107a expression in a biospecimen.
Tests
The determination of cellular CD137 expression in a biospecimen.
Tests
The determination of the amount of CD33 expressing cells per unit present in a sample.
Tests
The determination of the amount of CD38 expressing cells per unit present in a sample.