Indicator Explainer
5'-Nucleotidase
5'-nucleotidase (574 aa, ~63 kDa) is encoded by the human NT5E gene. This protein is involved in the conversion of nucleotides to nucleosides.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C114927. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — 5'-Nucleotidase (C114927)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C114927. NCI definition, reproduced without modification under CC BY 4.0.
- Basophilic Stippling Unmasks Pyrimidine 5'-Nucleotidase Deficiency in a G6PD-Deficient Patient. — Am J Hematol, 2026-09-10 (PMID 42719883; literature)
- Monomethylation of cytosolic 5'-nucleotidase 1A affects its recognition by inclusion body myositis autoantibodies. — J Neuromuscul Dis, 2026-09-02 (PMID 42684297; literature)
- Discovery of LB10, a Potent and Orally Bioavailable Inhibitor of Ecto-5'-Nucleotidase as a Single Agent or in Combination for the Treatment of Lung Cancer. — J Med Chem, 2026-10-01 (PMID 42911694; literature)