Glossary Term
Homozygosity
Having two identical allelic forms of a gene, one inherited from each parent, on each of the two homologous chromosomes.
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Glossary Term
Having two identical allelic forms of a gene, one inherited from each parent, on each of the two homologous chromosomes.
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This gene plays a role in signal transduction and cellular communication.
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This gene plays a role in carbohydrate metabolism.
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This gene plays a role in intermediary metabolism.
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This gene is involved in protein phosphorylation.
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This gene is involved in B-cell and T-cell maturation.
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Interleukin-1 beta (269 aa, ~31 kDa) is encoded by the human IL1B gene. This protein is involved in the macrophage-dependent inflammatory response.
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Interleukin-18 (193 aa, ~22 kDa) is encoded by the human IL18 gene. This protein is involved in the regulation of both natural killer cell activity and the production of interferon gamma.
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Interleukin-2 (153 aa, ~18 kDa) is encoded by the human IL2 gene. This protein is involved in T-cell proliferation, leukocyte stimulation and immune responses.
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Interleukin-4 (153 aa, ~17 kDa) is encoded by the human IL4 gene. This protein is involved in the regulation of the expression of class II MHC molecules, Fc receptors and cell surface-bound immunoglobulins.
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Interleukin-5 (134 aa, ~15 kDa) is encoded by the human IL5 gene. This protein plays a role in the growth and differentiation of both B-cells and eosinophils.
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Interleukin-8 (99 aa, ~11 kDa) is encoded by the human CXCL8 gene. This protein is involved in chemotaxis and neutrophil activation.