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A family of homotetrameric cytoplasmic enzymes involved in the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
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A lipoprotein that carries cholesterol around the body, for use by various cells. LDL transports cholesterol to the arteries and increased levels are associated with atherosclerosis, and thus myocardial infarctions and strokes. This is why cholesterol inside LDL lipoproteins is called bad cholesterol.
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A heterodimeric glycoprotein hormone secreted by the gonadotropic cells of the anterior pituitary gland. This hormone is involved in stimulation of testosterone production by Leydig cells in males and triggering ovulation and corpus luteum development in females.
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This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation.
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This gene plays a role in both protein phosphorylation and signal transduction.
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This gene plays a role in mediating cellular responses to growth factors, metabolic stimuli and mitogens.
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This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.
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This gene plays a role in epidermal development and regulation of melanogenesis.
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This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.
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This gene plays a role in both cell cycle arrest and the inhibition of apoptosis.
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A naturally occurring trace metalloid element and known neurotoxin with atomic symbol Hg, atomic number 80, and atomic weight 200.59. Mercury has been used in manufacturing, as well as in dental and medical equipment, fertilizers, and pesticides. It is characterized as a heavy, silvery-white metallic liquid at room temperature that is odorless. Exposure occurs by inhalation of fumes, ingestion, or contact.
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This gene plays a regulatory role in the modulation of cell-surface receptors and hepatocyte growth factor interactions.