Indicator Explainer
Lactate Dehydrogenase
A family of homotetrameric cytoplasmic enzymes involved in the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. In vertebrates, genes for three different subunits (LDH-A, LDH-B and LDH-C) exist.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C25184. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Lactate Dehydrogenase (C25184)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C25184. NCI definition, reproduced without modification under CC BY 4.0.
- Pretreatment lactate dehydrogenase, but not magnesium or neutrophil-to-lymphocyte ratio, is independently associated with grade ≥3 chemotherapy toxicity in breast cancer: prediction-model development and internal validation in 400 patients. — Cancer Treat Res Commun, 2026-10-07 (PMID 42843252; literature)
- Lactate dehydrogenase activity and carbohydrate metabolism under vanadium citrate exposure: Sex- and dose-dependent effects in rat tissues. — PLoS One, 2026-10-06 (PMID 42837355; literature)