Indicators
JAK3 Gene
This gene plays a role in signal transduction and non-receptor tyrosine protein kinase activity.
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Indicators
This gene plays a role in signal transduction and non-receptor tyrosine protein kinase activity.
Indicators
This gene is involved in ubiquitin-mediated protein degradation.
Indicators
The levorotatory isomer of the aromatic amino acid tyrosine. L-tyrosine is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine. It is considered a non-essential amino acid; however, in patients with phenylketonuria who lack phenylalanine hydroxylase and cannot convert phenylalanine into tyrosine, it is considered an essential nutrient. In vivo, tyrosine plays a role in protein synthesis and serves as a precursor for the synthesis of catecholamines, thyroxine, and melanin.
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Lactotransferrin (710 aa, ~78 kDa) is encoded by the human LTF gene. This protein is involved in the mediation of both proteolysis and iron transport.
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Leptin (167 aa, ~16 kDa) is encoded by the human LEP gene. This protein is secreted by adipocytes and plays a role in the regulation of both appetite and body fat stores.
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One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. Leucine also prevents breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. Leucine is available in many foods and deficiency is rare. (NCI04)
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Lipoprotein lipase (475 aa, ~53 kDa) is encoded by the human LPL gene. This protein is involved in the metabolism of triglycerides.
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An alkaline earth metal, Magnesium is important for many biochemical functions and reactions; for bone and muscle function, protein and fatty acid formation, activation of B vitamins, blood clotting, insulin secretion, and ATP formation. More than 300 enzymes require magnesium for catalytic action. The adult daily requirement is about 300 mg/day. Magnesium is found in many green plants, vegetables, and seeds; chlorophyll is a magnesium-centered porphyrin compound. Magnesium salts are used for magnesium deficiency supplementation. (NCI04)
Indicators
This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation.
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This gene plays a role in both protein phosphorylation and signal transduction.
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This gene plays a role in mediating cellular responses to growth factors, metabolic stimuli and mitogens.
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This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.