Glossary Term
Background
Existing conditions, especially those that would be confused with the phenomenon to be observed or measured.
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Glossary Term
Existing conditions, especially those that would be confused with the phenomenon to be observed or measured.
Tests
A bacteria culture test can determine if you have a bacterial infection and, if so, which type of bacteria is causing it. To do a bacterial culture test, you will need to give a sample of your blood, urine, skin, or other tissue. The type of sample depends on where the infection is located.
Indicators
This gene is involved in cellular growth regulation and is purported to have tumor suppression activity.
Glossary Term
Initiation of DNA base excision repair (BER) involves a DNA glycosylase that binds the altered deoxynucleoside in an extrahelical position and catalyzes cleavage of the base-sugar bond. Subsequently, an AP endonuclease or AP lyase activity incises the abasic site, followed by short-patch gap-filling, excision of the base-free sugar-phosphate residue, and ligation.
Glossary Term
A starting point to which things may be compared.
Tests
A basic metabolic panel (BMP) measures eight different substances in your blood. It provides important information about your body's fluid balance , your metabolism (the process your body uses to make energy from food you eat), and how well your kidneys are working. This test is often used to check your general health.
Indicators
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Indicators
This gene is involved in transcriptional repression and plays a role in the modulation of B-cell responses.
Indicators
This gene plays a role in the repression of gene transcription.
Tests
A BCR-ABL1 genetic test uses a sample of blood or bone marrow to look for an abnormal gene called BCR-ABL1. This abnormal gene is found in certain types of blood cancer , such as chronic myeloid leukemia (CML).
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Glossary Term
A sequential p-value procedure that controls expected false discovery rate.