Indicator Explainer
Hydroxyprogesterone
A physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor mediated gene expression.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C87242. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Hydroxyprogesterone (C87242)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C87242. NCI definition, reproduced without modification under CC BY 4.0.
- [Establishment and validation of an LC-MS/MS-based determination method for 17-hydroxyprogesterone in canine serum]. — Tierarztl Prax Ausg K Kleintiere Heimtiere, 2026-08-19 (PMID 42618022; literature)
- The Real-World Safety Profile of Hydroxyprogesterone: A Pharmacovigilance Study Based on the Food and Drug Administration's Adverse Event Reporting System Database. — Drug Res (Stuttg), 2026-08-04 (PMID 42551849; literature)