Indicator Explainer
Gentamicin
A broad-spectrum aminoglycoside antibiotic produced by fermentation of Micromonospora purpurea or M. echinospora. Gentamicin is an antibiotic complex consisting of four major (C1, C1a, C2, and C2a) and several minor components. This agent irreversibly binds to the bacterial 30S ribosomal subunit. Specifically, this antibiotic is lodged between 16S rRNA and S12 protein within the 30S subunit. This leads to interference with translational initiation complex, misreading of mRNA, thereby hampering protein synthesis and resulting in bactericidal effect. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C519. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Gentamicin (C519)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C519. NCI definition, reproduced without modification under CC BY 4.0.
- Antibiotic prophylaxis with vancomycin and gentamicin and the occurrence of acute kidney injury after cardiac surgery with cardiopulmonary bypass: A retrospective single-centre cohort study. — Eur J Anaesthesiol, 2026-10-20 (PMID 42900675; literature)
- Development of an Injectable Boronic Ester Nanocomposite Hydrogel for pH- and Thermo-Responsive Gentamicin Delivery and Antibacterial Activity. — AAPS PharmSciTech, 2026-10-15 (PMID 42881279; literature)
- Surface-localized thermoresponsive molecularly imprinted polymer for gentamicin recognition and aqueous regeneration. — RSC Adv, 2026-10-22 (PMID 42923855; literature)
- Immunohistochemical Insights into Enhanced Burn Wound Healing by Poly(vinyl alcohol)/Gentamicin and Poly(vinyl alcohol)/Chitosan/Gentamicin Hydrogels. — Gels, 2026-10-14 (PMID 42929959; literature)
- Telmisartan attenuates gentamicin-induced ototoxicity and modulates oxidative stress and RhoA/ROCK-associated signaling in mice. — Neurosci Lett, 2026-10-26 (PMID 42933717; literature)